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A recent publication by researchers from The Pirbright Institute and the University of Southampton demonstrate the expression of cattle DL-Lineage KIR on various immune cell types, including B cells and monocytes, in addition to the conventionally observed expression limited to T cells and NK cells in primates.
The UK Immunological Toolbox project at Pirbright has developed and validated a high throughput workflow for sequencing hundreds of hybridoma clones. The workflow employs a universal method that allows sequencing of any hybridoma clone. Just under 400 hybridomas producing antibodies against a range of host species and viral pathogens have been sequenced (cattle; 200, chicken; 100, viruses; 50 and pig;15).
